Many songs on the game have songs that interpolate or sample them, which are also in the game, or featured in other GTA games.

Various intros, outros and comments are delivered by Barbara Fox.

Area 53: A Coast to Coast AM spoof hosted by Marvin Trill (Bob Sevra).

Lonely Hearts: Relationship advice program hosted by Christy MacIntyre (Sara Moon).

I Say/You Say: Political debate show hosted by husband-and-wife liberal-and-conservative team of Peyton Phillips (Paul Ames) and Mary Phillips (Jackie Hoffman).

Gardening with Maurice: Gardening show hosted by Maurice (Andy Dick).

Entertaining America: Entertainment program hosted by Billy Dexter (Peter Marx) and Lazlow, featuring various guests.

The Wild Traveler: Travel program hosted by James Pedeaston (Sam Tsoutsouvas).

The Tight End Zone: Sports program hosted by Derrick Thackery (Peter Appel).

WCTR News: Hosted by Lianne Forget (Sharon Washington) with Richard Burns (Wil Wheaton), which features up-to-date news in the San Andreas state.

The following programs can be heard on the station:

West Coast Talk Radio, abbreviated as WCTR, is a talk radio station headquarted in Los Santos. The songs are listed in the same order as they appear in the game manual. User Track Player (PC and Xbox only) - User-Defined Track Player.The player can listen to the following radio stations: The standalone version of the soundtrack was released on November 23, 2004. Together with several early-1990s music, the scores of the soundtrack also included songs from the 1960s, 1970s and 1980s. The soundtrack of Grand Theft Auto: San Andreas, which is set in 1992 at the West Coast state of San Andreas, required that the game's radio stations reflect the music tastes of the time and area, in addition to covering current events in the state of San Andreas.

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